Dr Holst studied dentistry at the Medical University of Hanover and obtained his doctorate in 2000 with the title of Dr. med. dent. From 2000 to 2001, he attended a postgraduate program in the Department of Prosthodontics at Louisiana State University, USA (Head: G. Chiche). Dr Holst was appointed assistant professor at the Dental Clinic 2 - Prosthodontics, Friedrich-Alexander-University Erlangen-Nuremberg Germany in 2001. In 2006, Dr Holst completed his habilitation thesis and obtained his Dr. med. dent. habil. (PhD equiv) degree from the University of Erlangen-Nuremberg. His field of specialization encompasses esthetic dentistry with an emphasis on implantology, perio-prosthetics and complex interdisciplinary treatments. His research work focuses primarily on the implementation of new optical measurement technologies for biomechanical analysis, the biomechanics of implant-borne superstructures and prosthodontic factors influencing peri-implant soft tissue. Since 2006, Dr. Holst was appointed clinical associate professor and senior lecturer and heads the interdisciplinary histology section at the Friedrich-Alexander-University Dental Clinic. He has authored several published papers on implant prosthodontics, esthetics and various prosthodontic subjects.